Cancer of the bladder has a bad reputation: the combination of urinary problems and malignancy gives just cause for continuing concern. Not only is this common cancer a burden to the patient but, because of the need for regular follow-up, it creates a large workload on the urological services. It might be imagined that the bladder would give early warning signals of disease, and indeed it may do so; yet it can also be hesitant to reveal its severity. Thus there are many problems that create challenges in the diagnosis and management. Prevention is still the first goal of an oncologist, with early detection of early disease being the next best option. Early bladder cancer is amenable to several therapeutic approaches, but we have still to determine the best approach. The management of more advanced invasive bladder cancer all too often leads to disappointment, and we remain uncertain as to the optimum approach-surgery, radiotherapy, chemotherapy or some combination of these. Although none of these problems may be fully answered either now or in the near future, many people are working towards their solution, and the rate of progress needs to be documented from time to time. This volume aims to set the standard for the present state of our knowledge on bladder cancer. The editors, Professor Ernst Zingg and Mr'. Michael Wallace, have gathered together the best opinions on a wide range of topics relating to bladder cancer.
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5-year survival adjuvant Adriamycin agents antigens assessment biopsy bladder cancer bladder carcinoma bladder wall Cancer Res carcinogens catheter chemotherapy cis-platinum classification Clin clinical cyclophosphamide cystectomy for bladder cystectomy specimen cystitis cystoscopy cytology cytotoxicity detection diagnosis disease dose Edsmyr F effective endoscopic examination follow-up grade haematuria histological hyperthermia immune implantation incidence infiltration instillation interferon intravesical intravesical chemotherapy irradiation laser lesions lymph nodes lymphocytes lymphography malignant metastases mucosa mucosal biopsies muscle neoplasms NK-cells normal palliative papillary partial cystectomy patients with bladder pelvic procedure prognosis prostate radiation radical cystectomy reported resection response risk Soloway squamous superficial bladder cancer superficial bladder tumours superficial tumours surgery symptoms technique therapeutic therapy thiotepa tissue transitional cell carcinoma transurethral treated treatment tumour cells tumour recurrence UICC upper tracts ureteric urethra urinary bladder urinary diversion urinary tract Urol urological urothelial carcinoma urothelium Wallace Werf-Messing Whitmore WF