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. In the year 876 Tinmouth was again ravaged by Halfden, the Danish king

During the reign of Athelstan, King of the West-Saxons, which began A. D. 924, and ended in 946, this monastery, then hardly secovered from its former desolation, was again ravaged by the Danes.

« It is no wonder that, after having been so often plundered and destroyed, this place should have lain 10 long in ruins that the re. membrance of King Ofwin, the sainted patron thereof, was utterly loft. :)

• After fome respite from the invasions of the Danish pirates, so whom its exposed situation on the sea coast rendered it an easy, and defenceleis prey; and who, by their repeated depredations, appear to "have left nothing that could induce them to return, the then bishop of the diocese obtained it of the Earls of Northumberland; and, after filling it anew with religious, restored therein the celebration of divine Tervice.

• It was not, however, till the latter end of the reign of Edward the Confeffor that the bones of the royal martyr St. Oswin were dis. covered.

« About the conclufion of this reign, which ended in 1966, the royal faint and martyr Ofwin, in one

of those dreams common to the times, is said to have appeard to Edmund, the fexton of this place, and pointed out to him the place of his own interment. Judith, wife of Tosti, Earl of Northumberland, gave credit to the sexton's vision, and ceased not to exert her influence with Egelwine, then bishop of Duro ham, till he had ordered a search to be made for the royal bones, which are said to have been discovered in an oratory, according to the saint's directions in the vision, on the 5th of the ides of March, A. D. 106.5, and 415 years after his death. The royal remains, after having been inclofed in a coffin, and honoured with every kind of funeral pomp, -were recommitted to the facred earth.

Tofi, Earl of Northumberland, according to some writers, re. built this monastery from the foundation.'

Mr. Brand afterwards gives the history of Newcastle, as a cor. porate town, or borough; which is detailed with great and uninteresting minuteness through the remaining part of the work, In respect of coal, for which this place has been long so much distinguished, he juftly observes, that though some writers have not scrupled to affirm that coal was unknown to the ancient Britons, yet others have contended for the contrary by almost irresistible arguments. The Britons, it appears, had a primitive "name for this foffil; and Mr. Pennant informs us that a flintax, the instrument of the aborigines of our island, was discovered ftuck in certain veins of coal, exposed to day, in Craig Park in Monmouthshire, and in such a situation as to render it very accessible to the unexperienced națives, who in early times' were incapable of pursuing the veins to any great depth. The


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strongest argument in favour of the opinion of those who think that the Romans, while in Britain, were ignorant of this commodity, is, that their language affords no name for it; the genuine and determinate fignification of carbo being charcoal. But the facts and testimonies adduced by our author afford much reafon to conclude that coal, though at first unnoticed in Britain by the Romans, was afterwards in actual use amongst them.

The second volume, like the first, is accompanied with an appendix, containing various documents relative to the subject of the history. It would be a task no less unproductive of gļatification to our readers than unnecessary, and indeed almost impoffible for us, to give a more particular account of this work. We have already expressed our disapprobation of the frivolous prolixity and jejune minuteness with which it has been indultriously executed; but we cannot conclude without acknowledging at the fame time, in justice to Mr. Brand, that he appears to have spared no pains in amaffing his extraordinary collection of materials; that he has preserved the historical detajl with uninterrupted exactness; and above all, that he has manifested, by the multiplicity of notes and references, a degree of learning, and an extent of inquiry, which, in a nobler field of historical research, might have crowned his labours with more than common approbation. We must not omit to mention, in -favour of the work, that it is embellished with a great number of well-executed engravings.

ART. VI. A Treatise of the Materia Medicn. By William

Cullen, M.D. Professor of the Practice of Physic in the University of Edinburgh, &c. &c. 4to. 2. vols. Il Is. 6d. boards.

Elliot and Kay. London, 1789. DR R. Cullen, it feems, from the success of his lectures on

the Materia Medica formerly, published in his name, though extremely incorrect, had entertained a design of giving a more accurate and complete edition of those lectures; but he afterwards, abandoned that idea, and has modelled the work into the form in which it now appears. As if he had purposely resolved to preclude incorrectness, as much as possible, by retrenchment, he has omitted a number of articles common in every treatise on this subject; and for these omiffions he proceeds to offer an apology, or rather a justification of his conduct:

In the first place, he informs us that he did not think it ne. cessary to detail the various nomenclature of the different subftantes, as it may be readily obtained elsewhere; and particularly


he has not attempted to ascertain the nomenclature of the ancients, both because of the difficulty that would attend such a labour, and because he is very doubtful of its utility.

In ascertaining the species of plants, where several of the same genus may be employed, he has likewise purposely omitted entering into any critical discussion respecting their comparative fuperiority; thinking it enough for him to have marked, in the catalogue prefixed to his treatile, the botanical distinction of the fpecies which he judged most fit to be employed.

Another omission, of a similar nature with the preceding, is the not giving any defcription of the particular medicines as they are employed, or fit to be employed. This, however, he acknowledges to have omitted because he could not do it so completely and accurately as the authors to whom he refers, and whom he supposes his readers to have in their hands.

The omiffion of the chemical analysis of the several substances he thinks, and very justly, will require no apology in the present age; but he doubts whether he shall be so easily forgiven for frequently omitting the treatment of substances by the application of different menftruums, and for not mentioning the quantities of extract that are obtained from each of them. He admits that an attention to these circumstances is very necessary in the pharmaceutic treatment of medicines; but he did not think it proper to increase the bulk of his work by details contained in books to which he refers, and which he wishes to recommend to all his readers. The books alluded to are the three following, viz. the Treatise of the Materia Medica by Dr. Lewis, as now published by Dr. Aikin; the Treatise of Petrus Jonas Bergius on the Materia Medica, taken from vegetables; and the Apparatus.Medicaminum by the learned professor of Gottingen, Jo. Andreas Murray, knight of the royal order of

Dr. Cullen's chief purpose in the present work is to give the principles upon which the various substances coinprehended in the Materia Medica are to be judged of as medicines; to correct the errors of former writers in that respect; and to offer fome new principles and doctrines which appear to him to be necessary. These doctrines are given partly in his general introduction, and partly in the refečtions on the general operation of medicines, prefixed to the several chapters.

Such is the general plan of the work now before us, and such the particular motives which have actuated this learned and industrious author in the esecution of it. We shall now proceed to give a concise account of its different parts.

After a general history of the Materia Medica, as it exists in the writings of the Greek and Arabian physicians, Dr. Cullen


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"с ENG. REV. VOL. XV. JAN. 1790.


traces the progress of this science, through the various authors on the subje&i, from the revival of learning in the fifteenth century to the present time. This part of the work discovers much reading and attentive observation; but the inferences deducible from the whole are chiefly that the Materia Medica, with all its accumulated acquisitions, has hitherto remained in a state of great imperfection; that superstition, both ancient and modern, obfervations too llight, and conclusions likewise too precipitate, had given rise to a multiplicity of errors, rendered venerable by long prescription; and, in short, that there was still a necessity for such a work as the present, to examine more strictly the mass of the Materia Medica, which has been reared by the ignorance of ages, and to establish the virtues of medicines by the only true and unerring test, that of accurate observation and experience. In endeavouring to perform this useful undertaking, Dr. Cullen evinces a scrupulous regard to fact, and a judgment too strong to be in the least degree influenced by the prejudice of authority; but, at the same time, we are of opinion that, though he has exercised his critical talents with much ability in examining the writings of former authors, he treats them, in some instances, with a severity of censure from which candour at least, if not justice, might have exempted them.

The author next proceeds to consider the action of medicines upon the body in general; concluding from obvious premises, that the peculiar effects of substances in general, or of those substances in particular which are called medicines, when applied to the human body, depend on their action upon its fentient and irritable parts. This naturally leads him to the confideration of temperaments, concerning which the theory of the ancient physicians has long since been deservedly'exploded. To treat this subject in a philosophical manner is a task attended with great difficulty, and would require very extensive, as well as minute observation. Dr. Cullen, therefore, instead of distinguish ing temperaments by marking the internal and observable cir cuinstances which are commonly combined together, proceeds to the inquiry in another way; and endeavours to consider those circumstances of the internal state of the human body which may give occasion to a difference in the state of the functions, and even in the external appearances which distinguith different anen, These circunstances our author refers to five general heads, according as they occur, ist. In the state of the timple solids ; 2dly. In the state of the fluids; 3dly. In the proportion of folids and fuids in the body; 4thly. In the distribution of the fuids; and, 5thly, In the state of the nervous power. Having treated of these several subjects, he next inquires into the nature of particular temperaments and idiosyncrasies; as these likewise



tend, though remotely, to account for the action of medicines upon the body in general.

In the second chapter of this part of the work the learned professor comes more immediately to the subject of pharmaceutical disquisition, and treats of the various means by which we arrive at the knowledge of the virtues of medicines. In prose. cuting this inquiry he examines into the use of chemical resolution in investigating the virtues of different substances; the use of botanical affinities in ascertaining the medical virtues of plants; the confideration of the sensible qualities of substances, as pointing out their medical virtues ; and, lastly, the knowledge of the virtues of medicines by experience.

Dr. Cullen, after giving a short account of the most proper plan for a treatise on the Materia Medica, presents us with a dictionary of the general terins employed by writers on that subject. This chapter, which includes the catalogue of medicinal substances, is of great length, and may indeed be considered as liable to the charge of redundancy. For the instances are fo few in which our author employs general terms in any peculiar acceptation, that either the latter might have been defined occafionally, when they occurred, or the dictionary been reduced to a very small number of articles.

We next meet with a copious treatise of aliments; which, after some observations on the cookery of meats, is followed by a chapter on drinks, succeeded by another of condiments. The article of which our author treats most copiously is that of milk, which he seems to have considered with more than common attention. As our limits will not permit us to detail the observations on this subject, we shall only mention that Dr. Cullen endeavours to invalidate the notion of the chyle alone affording the matter of milk, immediately on its reception into the blood-vessels ; a doctrine which we think he impugns by strong arguments, founded upon facts and the established principles of physiology.

Our ingenious author, having finished all his preliminary subjects, introduces us to the Materia Medica in the beginning of the second volume, through the whole of which it extends. He distinguishes medicines into the various classes usual in systems of this kind; and prefixes to each chapter an account of the mode of operation assigned to the particular class of which they respectively consift. The first is the tribe of astringents, confidered by Dr. Cullen as distinct from that of the tonics, which forms the second chapter of the volume. Next follow emollients, corrosives, stimulants, sedatives, refrigerants, antispalmodics, &c. If we except the Peruvian bark, opium, camphire, mercury, and a few other articles, of which our author treats

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