Cancer Chemotherapy and Biotherapy: Principles and PracticeLippincott Williams & Wilkins, 7 gru 2011 - 848 Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank. |
Spis treści
Chabner_Chap43 | 773 |
Chabner_Chap21 | 419 |
Chabner_Chap22 | 442 |
Chabner_Chap23 | 459 |
Chabner_Chap24 | 462 |
Chabner_Chap25 | 465 |
Chabner_Chap26 | 495 |
Chabner_Chap27 | 511 |
Chabner_Chap18 | 356 |
Chabner_Chap19 | 392 |
Chabner_Chap20 | 411 |
Chabner_Chap37 | 685 |
Chabner_Chap38 | 708 |
Chabner_Chap39 | 722 |
Chabner_Chap40 | 732 |
Chabner_Chap41 | 746 |
Chabner_Chap28 | 517 |
Chabner_Chap29 | 526 |
Chabner_Chap30 | 547 |
Chabner_Chap08 | 107 |
Chabner_Chap09 | 139 |
Chabner_Chap10 | 171 |
Chabner_Chap11 | 192 |
Chabner_Chap12 | 210 |
Chabner_Chap13 | 216 |
Chabner_Chap14A | 267 |
Chabner_Chap14B | 293 |
Chabner_Chap15 | 310 |
Chabner_Chap16 | 323 |
Chabner_Chap17 | 342 |
Chabner_Chap31 | 577 |
Chabner_Chap32 | 605 |
Chabner_Chap33 | 618 |
Chabner_Chap34 | 632 |
Chabner_Chap01 | 1 |
Chabner_Chap02 | 15 |
Chabner_Chap03 | 28 |
Chabner_Chap04 | 50 |
Chabner_Chap05 | 62 |
Chabner_Chap06 | 80 |
Chabner_Chap07 | 96 |
Chabner_Chap35 | 649 |
Chabner_Chap36 | 674 |
Inne wydania - Wyświetl wszystko
Cancer Chemotherapy and Biotherapy: Principles and Practice Bruce A. Chabner,Dan L. Longo Ograniczony podgląd - 2010 |
Cancer Chemotherapy and Biotherapy: Principles and Practice Bruce A. Chabner Podgląd niedostępny - 2015 |
Kluczowe wyrazy i wyrażenia
acid action activity acute addition administration agents alkylating antibody antitumor appears associated bevacizumab binding Biol bleomycin Blood breast cancer cancer cells Cancer Res carcinoma cells cellular chemotherapy cisplatin clearance Clin Oncol clinical combination compared complex concentrations cytotoxic decrease demonstrated disease dose drug effects enhanced enzyme et al evaluated exposure expression factor function gene given growth half-life high-dose higher human ifosfamide imatinib important increased induced infusion inhibition inhibitors interactions intravenous kinase leads less leukemia levels lung lymphoma malignancies mechanism mediated metabolism metabolites metastatic methotrexate microtubule mutations normal occurs Oncology oral ovarian paclitaxel pathway patients pharmacokinetics Pharmacol phase plasma potential produced protein receiving receptor reduced regimens renal repair reported resistance response risk role schedule sensitivity signaling solid specific suggest Table therapy tion tissue toxicity transport treated treatment trial tumor versus vincristine vitro