Group Antigens in Human Organs
Blood Transfusion Division, U.S. Army Medical Research Laboratory, 1970 - 142
The monograph, which was originally published in German in 1941, deals with the important problem of the occurrence of blood group specific antigens in the tissues of man. A careful quantitative study with a mathematical analysis was carried out using two basic methods--the inhibition of isoagglutination for the presence of water-soluble group specific antigens and the complement fixation method for the demonstration of both alcohol-soluble and water-soluble group specific substances. The treatise presents further experimental proof that the antigens representing the A and B substances are not limited to the red blood cells but occur in most organs of the body with the possible exception of the brain.
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according actual alcoholic extracts amount anti anti-A antigen concentration aqueous average bile bladder blood corpuscles Blood group boiled Chapter compared comparison complement complement-fixation complete comprising considered contain corresponding course curves destruction determined diagrams difference discussion distinct distribution employed enzymes established examined excretion exhibit experiments explained extracts fact Figure Friedenreich further gastric juice given glands group antigen human indefiniteness indeterminacy indicated inhibition jejunum kidney latter liver material means measured method non-secretor R.H. Number of Individuals observations obtained Oo Oo Oo organs original pancreas persons phenomenon possible present production psoas major question random regard represent saline saliva samples Schiff secretions secretor R.H. secretors and non-secretors sera serum standard deviation stomach subjects submaxillary gland substances Table taken theory tion titer reading titer scale tube types uncertainty urine values various water-soluble antigen